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[11] [12] [13] No medical uses for MSM have been approved and there is limited evidence to support most of the claims

L.RehmanM.WaltherT
Sun Y, Huang H, Zhan Z, et al
Some scholars have discovered by knocking out the mouse SQSMT1 gene that SQSTM1 mediates ULK1 phosphorylation to activate autophagy and promote the formation of AMPK-ULK1-SQSTM1 complex, which leads to autophagic Keap1 degradation and activates the non-canonical Keap1-Nrf2 pathway, thereby protecting mouse liver from lipotoxicity (Figure 4) (Lee et al., 2020)

Tri-stimuli-responsive biodegradable theranostics for mild hyperthermia enhanced chemotherapy

A.KlochkovS
