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Despite the significant increase in the ABR threshold, the rate of OHC loss remained relatively modest, indicating that synaptic and neural damage preceded substantial hair cell loss in this model

Kulkarni et al., 2017)

The main proteins responsible are sulfhydryl oxidases, which often incorporate iron, copper, or flavin binding domains to participate in oxidation-reduction reactions (Kodali and Thorpe, 2010)

Biotechnological Approaches and Therapeutic Potential of Mitochondria Transfer and Transplantation

Ozkisacik, S., Yazici, M., Gursoy, H., Serter, M

The tumor may present with well-defined borders and a fibrous capsule, but at least capsular or vascular invasion is typically present