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In contrast, ethanol-mediated inhibition of SIRT1 disrupts the lipid-1 pathway, leading to steatosis through an altered lipid-1/ ratio (Yin et al., 2014)

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Alterations in the neuronastrocyte partnership have emerged in the literature and have been shown to underlie brain lesions in pathologies as varied as brain tumors, Alzheimer's disease, and amyotrophic lateral sclerosis [413]

[DOI] [PubMed] [Google Scholar] 136.Bailey S.M

Together, these systems ensure the precise spatiotemporal control of zinc concentrations, preventing both deficiency and cytotoxic excess