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Insulin resistance and acne: the role of metformin as alternative therapy in men

A cell under chronic oxidative bombardment sustains protein damage, mitochondrial DNA mutations, and lipid peroxidation

Geffroy G, Benyahia R, Frey S, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Inisan A et al (2018) The accumulation of assembly intermediates of the mitochondrial complex I matrix arm is reduced by limiting glucose uptake in a neuronal-like model of MELAS syndrome

Aging Liu and coworkers have systematically evaluated the effect of aging in rodents on GSH homeostasis in different tissues and found that GSH level falls in all tissues with age, due to a corresponding fall in GCL and GS gene expression (no change in GGT, GSH reductase expression, cysteine availability or GSSG as an indicator of oxidative stress) (Wang et al., 2003

Acta Myol 30(1):1623 Jun JC, Rathore A, Younas H, Gilkes D, Polotsky VY (2017) Hypoxia-inducible factors and cancer

Your brain doesn't see any leptin, thinks you're starving and works very hard to make you eat more
