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The safety profile is strong: toxic doses sit roughly 300 to 3,750 times higher than recommended therapeutic amounts, and injection site irritation remains the most commonly reported side effect

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found that the abnormal accumulation of double-stranded DNA in the cytoplasm may bind to the cytoplasmic DNA sensor (cGAS), thereby specifically triggering the STING-interferon (IFN) signaling pathway in microglia, promoting the expression and secretion of inflammatory cytokines

[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Cho M., Lee T.Y., Kwak Y.B., Yoon Y.B., Kim M., Kwon J.S

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The presence of benzyl alcohol allows the solution to remain bacteriostatic, supporting repeated vial access when proper aseptic techniques are consistently followed
