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Folic acid is not a substitute for vitamin B12 although it may improve vitamin B12 deficient megaloblastic anemia

With more NAD+ available, a chain of energy-sensing switches (SIRT1, PGC-1) turns on, prompting cells to build more mitochondria and burn more fat for fuel

J Paediatr Child Health 54:900906

The recruitment of neutrophils and monocytes/macrophages then occurs with amplification of the acute inflammatory response, followed by the proliferation and activation of the effector cells to re-establish the barrier function and to induce neoangiogenesis

It has demonstrated the ability to promote recovery