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Description
It has higher incidence in Scandinavian populations, shares risk factors with Parkinsons disease and Alzheimers diseases and was associated with mutations in the lysyl-oxidase-like 1 (LOXL1) gene, and mutations in loci encoding CACNA1A, TMEM136, SEMA6A and other genes
Some may support the release of brain-derived factors that protect neurons
Both caffeine and nicotine are stimulants that stimulate sympathetic nervous system arousal
10.1002/cpt.2627 Clin Pharmacol Ther
[DOI] [PMC free article] [PubMed] [Google Scholar] Borges, U
doi: 10.1007/10_2013_243 150 PaterakiI.SanmartinM.KalamakiM
