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doi: 10.1016/j.coph.2019.04.008 25 DavidL
These first generation direct-acting antivirals offered a more sustained virological response, especially among those with genotype 1, as well as a shorter duration of treatment, and fewer adverse effects
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0.04 g MC4R antagonist per side)
The cyclic structure makes MT2 much more stable than even MT1, but more importantly, it dramatically altered its ability to bind to the melanocortin receptors
