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Early timely treatment is crucial for CACTD and may reverse the metabolic decompensation

Silica also contributes to bone strength by enhancing the formation and maintenance of connective tissue and bone matrix

In addition to vasoprotection, oral administration of quercetin-3- O -gentiobiose (2575 mg/kg) once daily for two weeks considerably improved the endurance capability of rats against fatigue, decreased serum blood urea nitrogen (BUN) and lactic acid levels, enhanced the activities of antioxidant enzymes (SOD, glutathione peroxidase) and attenuated inflammatory cytokine levels (MCP-1, IL-6 and TNF-)

A Mann-Whitney test was used to assess differences between groups