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4.3 Clinical research on WMT for ASD Currently, FMT is not only used to treat gastrointestinal diseases such as inflammatory bowel disease, irritable bowel syndrome, functional constipation, and cirrhosis but has also been applied to neuropsychiatric disorders (e.g., ASD, anxiety, depression, and Parkinsons disease), metabolic diseases (e.g., diabetes, obesity, fatty liver, and hyperlipidemia), and immune-related conditions (e.g., cancer immunotherapy, allergic diseases, and chronic fatigue syndrome), demonstrating promising clinical efficacy (Ye et al., 2020)

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The main negative lifestyle habits and environmental conditions affecting male fertility include an inadequate diet leading to obesity, air pollution, exposure to harmful chemicals (food and drinks, agricultural and industrial products), exposure to heat, cigarette smoking, alcohol intake, stress, inadequate physical activity, and use of mobile telephones and portable computers [6,7,11]

Identifying who is at higher risk of developing OIPN would thus be an important step forward

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