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In I/R + M group, meldonium restores hepatic antioxidative defence mostly through reverse changes relative to those induced by I/R, i.e., through the CuZnSOD and MnSOD activity increases by 50%, the GSH-Px activity and GSH content increase 2.5-fold, and the GST activity decreases by 10% (Table 3)

Development of several experimental treatments have been initiated in the last number of years including pharmacological intervention and gene therapy, though comparisons of intervention efficacy across different trials is significantly hindered by different groups utilizing different outcome measures

Xidlike phenotypes: a B cell signalosome takes shape

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397 In the nematode Caenorhabditis elegans , overexpression of ATGL or muscle-specific activation of protein kinase A extends lifespan

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