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In contrast, nearly 25% of patients with UC do not respond to biologics and almost 60% of patients eventually lose their response[43]

doi: 10.3389/fendo.2022.882241 8 DengJZongZSuZChenHHuangJNiuYet al

It promotes cell migration to the injury site, downregulates inflammation, and is particularly noted for its ability to improve flexibility in damaged tissues

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However, the difference is that many respiratory mutants with higher AsA level and enhanced ROS show tolerance to abiotic stress whereas the low AsA mutants are stress- sensitive