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visible skin or hair changes, when they occur, typically build gradually over weeks to months rather than overnight

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PMID: 37686597

This method is particularly effective for patients who have difficulty absorbing B12 from food or pills due to conditions like pernicious anemia, Crohns disease, celiac disease, or post-gastrointestinal surgery
Increased oxidative damage in peripheral blood correlates with severity of Parkinsons disease
They can suffer much earlier and more severe deficiencies from the outset, and the disaster that a B12 problem can cause for young children is well documented in the scientific literature through reported cases