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Though historically considered weak compared to C3a and C5a, C4a exerts direct biological effects including endothelial cell activation, increased vascular permeability, and mast cellindependent smooth muscle contraction

Serum mercury concentration in relation to survival, symptoms, and diseases: results from the prospective population study of women in Gothenburg, Sweden

In SLE patients, depletion of glutathione has been associated with various immune abnormalities including deregulation of apoptosis, abnormal cytokine and chemokine production and various clinical features
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29 IidaK.ItohK.KumagaiY.OyasuR.HattoriK.KawaiK.et al (2004)