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Prolonged folic acid therapy may result in decreased vitamin B12 serum levels

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[DOI] [PMC free article] [PubMed] [Google Scholar] 78

On the other hand, it would seem that a lack of vitamin B12 can cause people to lose their appetite, resulting in a decrease in weight rather than an increase in weight

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Animal studies have shown that when beta-3 adrenergic receptors were genetically removed, chronic AOD-9604 treatment produced no changes in weight or lipolysis, confirming the importance of this pathway