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It was proposed that the increasing accumulation of the -amyloid precursor protein and -amyloid peptide caused GAPDH oxidation

Improved motor co-ordination in Scopoletin treated park 13 flies To test whether the improvement in neuronal abnormalities translated to rehabilitation of aberrant movement phenotypes including motion slowness, difficulties with gait and balance, we utilized the negative geotactic and phototactic behavior of Drosophila flies

To further reinforce that YFH1/FXN is essential in iron metabolism and mitochondrial function in eukaryotic cells, YFH1 overexpression rescues a growth defect of bm-8 mutant yeast cells which are unable to grow on iron-deplete media (Gonzalez-Cabo et al., 2005)

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KEGG analysis disclosed that the up-regulated genes were mainly enriched in members of the JAK-STAT signaling pathway, which is the TOP 5 items of KEGG (Fig