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1,N2-propanodeoxyguanosine adducts: potential new biomarkers of smoking-induced DNA damage in human oral tissue

Continual oxidative insult creates a decline in DNA repair machinery including base-excision repair (BER) and mismatch repair (MMR) and promotes mtDNA mutations (Leandro et al., 2015)

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How mammalian cells acquire copper: an essential but potentially toxic metal
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WHATS THE DIFFERENCE

NSCLC is frequently associated with an upregulation of epidermal growth factor receptor (EGFR) and programmed deathligand 1 (PDL1), where the former promotes tumour survival and the latter prevents cancer cells from immune detection
