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Chi dovrebbe evitare o assumere con cautela: Soggetti con patologie renali Persone con disturbi tiroidei Chi assume terapie farmacologiche croniche Donne in gravidanza o allattamento Soggetti con storia di crisi convulsive Possibili effetti collaterali includono disturbi gastrointestinali e, raramente, odore corporeo intenso

2 Introduction Diabetic neuropathy is the incremental reduction in nerve fiber function as a result of exposure to elevated blood sugar levels (typically, over many years in type 1 diabetes, and sometimes after only a relatively short time in type 2 diabetes)

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doi: 10.1136/heartjnl-2016-309458

BDK inhibition by phenyl butyrate reverses this effect (Xue et al., 2017), suggesting that BDK could be a suitable target in the prevention of these cancers

(5) Kitano Y, Hashimoto S, Matsumoto H, Yamochi T, Yamanaka M, Nakaoka Y, Fukuda A, Inoue M, Ikeda T, Morimoto Y
