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The first step in serine biosynthesis is catalyzed by phosphoglycerate dehydrogenase (EC 1.1.1.95), which oxidizes 3-phosphoglycerate to 3-phosphohydroxypyruvate while reducing NAD + to NADH

Furthermore, in-vitro exposure to comparable concentrations of PS reduced bovine sperm motility and impaired blastocyst development, with evidence of increased formation of ROS and apoptosis (125)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Hope VD, McVeigh J, Marongiu A, Evans-Brown M, Smith J, Kimergard A, Croxford S, Beynon CM, Parry JV, Bellis MA, Ncube F

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Schneider HJ, Friedrich N, Klotsche J, Schipf S, Nauck M, Vlzke H, et al