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10.1002/mus.25733 22 BillichA.BornancinF.DvayP.MechtcheriakovaD.UrtzN.BaumrukerT

p62-Keap1-NRF2-ARE pathway: a contentious player for selective targeting of autophagy, oxidative stress and mitochondrial dysfunction in prion diseases

doi: 10.1038/s41416-019-0660-x 52 ErdelyiKDitroiTJohanssonHJCzikoraABalogNSilwal-PanditLet al

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Slides were then incubated in an acid denaturation solution (0.08 N HCl) for 7 min at room temperature, followed by a lysis solution (containing 2.5 M NaCl, 100 mM EDTA, 10 mM Tris-HCl, and 1% SDS
G6PD, via the pentose phosphate pathway, supplies NADPH to recycle GSH
