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In vivo studies link the effects of CPZ not only on demyelination and the death of oligodendrocytes, but also to the concurrent activation of microglia and astrocytes, in turn leading to an elevation in cytokine production (Buschmann et al., 2012

This compatibility may result in more predictable dose-response relationships and reduced potential for drug-drug interactions

This reading is then converted into a blood alcohol concentration

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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.MacFabe DF, Cain NE, Boon F, et al

Mck et al., 2021), demyelination is a constant finding in both white and gray matter regions pointing to the myelinating unit (the myelin sheath and oligodendrocyte) as a key target in this disease