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At higher concentrations, NO has an indirect effect through oxidative stress, leading to nitrosative modification of both proteins and lipids

One 2014 study found that anxiety disorders may have a solid link to oxidative imbalance and low glutathione levels in the brain

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doi: 10.1016/j.jicc.2017.06.017

Furthermore, the study results demonstrate that GSH treatments significantly reduce ROS accumulation in ethanol-treated HepG2 cells and in vivo models, highlighting their potential in mitigating alcohol-induced oxidative stress

Selenium biofortification in food crops: key mechanisms and future perspectives