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No Phase 2 or Phase 3 RCTs have been conducted in healthy adults for cognitive enhancement

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It is true for individuals whose diet or lifestyle prevents them from absorbing enough nutrients, such as those who eat plant-based diets that are naturally low in vitamin B-12 or have celiac disease

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[38, 39, 40, 41] This approach produces neutralizing antibodies (nAbs) against these proinflammatory biomolecules to inhibit their activities

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Vitamin B12 (cobalamin) plays an essential role in red blood cell formation, cell metabolism, and nerve function

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Without adequate intake of B12, vegans can easily develop deficiency over time, leading to symptoms such as fatigue, weakness, constipation, loss of appetite, weight loss, and nerve problems therefore the researchers recommend that vegans and vegetarians should add vitamin B12 to their diet by eating fermented foods, particular types of mushroom that contain the vitamin and B12-enriched vegetables

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