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For instance, Khavinson and colleagues (2003) found that Epitalon increased the lifespan of fruit flies, while Anisimov et al

Furthermore, the increased Tau protein and excitotoxicity in methyl-CpG-binding protein 2 neurons and astrocytes may be caused by an imbalance in glutamate homeostasis [153]

There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, possible folate deficiency, or concomitant use of other drugs

Exp Toxicol Pathol 64:487493 Seidman MD, Ahmad N, Bai U (2002) Molecular mechanisms of age-related hearing loss

however, significant discrepancies were observed at the species level

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