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The expression levels of the pro-apoptotic XAF-1 gene modulate the cytotoxic response to Nutlin-3 in B chronic lymphocytic leukemia

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Water intake was calculated as the difference between the final volume measured and the remaining volume over 24 h

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Rumbold A., Ota E., Hori H., Miyazaki C., Crowther C.A

The cell detection tool was used on the DAPI channel to make sure that only a cell was recognised and not the background or artefact by system

The upregulated expression of ptgs2a and acsl4a induced by FAC treatment, which was subsequently downregulated after DFO intervention, combined with the distinct expression pattern of gpx4a , may suggest that the mechanism underlying FAC-induced ferroptosis is different from that of Erastin, and the mode of ferroptosis rescue by DFO also differs from that of Fer-1