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BDNF small peptide mimetic, Peptide B-5, induced the expression of neuronal markers, as well as BDNF and its receptor TrkB, in primary hippocampal neuronal cultures indicating an enhanced neurotrophic effect [55]

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These enzymes excise the C-peptide, thereby generating the mature form of insulin, a small protein consisting of an A-chain of 21 amino acids (containing an internal disulfide bridge) linked by two disulfide bridges to a B-chain of 30 amino acids

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