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They counteract the inability to initiate movement and catalepsy (muscular rigidity and fixed posture regardless of external stimuli), which in turn results in significantly reduced dopaminergic cell activity that is involved in the direct pathway of movement

Nature 476 , 341345 (2011)

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Kim J., Hong S

Oxygen toxicity and reactive oxygen species: The devil is in the details

drug toxicity and adverse effects , which discusses mechanisms for adverse effects produced both during normal drug therapy and after an overdose, Drug toxicity and adverse effects There is no consistent use of terminology in describing effects of drugs that were not intended when the drug was prescribed

The Math Behind the Mix: Calculating Ratios for a 10mg Vial Alright, let's get down to the numbers