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Additionally, for those with severe asthma, when inhaled corticosteroids or other long-term asthma medications dont seem to be effective, bronchial thermoplasty may be used

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In active demethylation, 5mC is converted into oxidized intermediates such as 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxycytosine (5caC), which can alter gene expression and cell function [337]

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[DOI] [PubMed] [Google Scholar] 28.Friedman M.Food browning and its prevention: an overview