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Researchers should avoid placing the vial in the coldest part of the refrigerator, such as directly against the back wall, where temperatures can fluctuate or dip low enough to affect solution stability
It is studied for its ability to stimulate collagen and elastin production, support tissue remodeling and wound healing, and modulate inflammation and oxidative stress

Normal fibroblasts treated with tretinoin produced more bFGF than did controls, and this might partially explain the clinically observed tightening effects of tretinoin

Older adults are at a higher risk

Zhu et al., 2021)
