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used the Broad Institute gene response database The Connectivity Map to identify the top molecules capable of reversing gene expression characteristic for metastatic colon cancer

1957 Jul-Aug;5(4):431-9

A typical sufferer would be a young growing reptile, kept indoors with no ultraviolet light supplementation and fed on a low-calcium diet e.g
While Nirenberg and team were using binding assays to try to capture the RNA-amino acid associations, Khorana approached it differently by synthesizing repeating dinucleotide and trinucleotide RNA polymers and seeing which amino acids ended up linked together in the resulting protein chain

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