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Since ADMA is endogenous inhibitor of eNOS and L-Arg/ADMA ratio determines eNOS activity [118], L-Arg supplementation is proposed to be particularly beneficial in patients with elevated ADMA levels, as supported by results of studies in animal models of hypercholesterolemia and arteriosclerosis [117]

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The findings showed that NSAIDs and epidural analgesia significantly reduced opioid consumption in the first 24 hours after surgery

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Hong H, Roy BC, Chalamaiah M, Bruce HL, Wu J
