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54 Pruritis and a rise in low-density lipoprotein cholesterol (LDL) are the two major concerns with the use of OCA

doi: 10.1038/ijo.2016.93 4 ArnoldM.NhoK.Kueider-PaisleyA.MassaroT.HuynhK.BraunerB.et al
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In the brain, apoE plays an important role in transporting cholesterol and other lipids to neurons through binding to cell-surface apoE receptors involved in lipoprotein metabolism, such as low-density lipoprotein receptor (LDLR), and LDLR-related protein 1 (LRP1) [46]

The body tissue distribution studies show a very high concentration of LC in mature spermatozoa and luminal fluid of cauda epididymis [26]

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Malik R., Sangwan A., Saihgal R., Paul Jindal D., Piplani P
