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Peptides, short chains of amino acids, control hormones and cell signals

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FOXO4-DRI works by disrupting the interaction between the FOXO4 protein and p53, enabling p53 to activate apoptosis in senescent cells

To understand the underlying mechanisms, inhibitors targeting the Notch pathway (DAPT) and NF-B pathway (BMS) were also applied to HUVEC and murine CLI models

Listen to Your Body While the science gives us a blueprint, your body is the ultimate laboratory