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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-

Under prolonged metabolic stress, it may progress to metabolic-associated steatohepatitis (MASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma, which are among the leading causes of end-stage liver disease and liver transplantation

This combination approach enhanced cytotoxic immune responses characterized by increased expression of IFN, TNF, and IL-10 [40]

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SCFAs switch stem cell fate through HDAC inhibition to improve barrier integrity in 3D intestinal organoids from patients with obesity
