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Indeed, among the factors contributing to the progression of ALD to ASH and cirrhosis, oxidative stress certainly plays a key role [133]

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These include hepatic and nervous tissues, as well as muscle, bone, and tendon

For example, the TM6SF2 E167K genotype associates with steatosis but not fibrosis, whereas MBOAT7 rs641738 is solely associated with increased fibrosis

Pharmacol Biochem Behav 27 : 665670

Mishra B, Reiling S, Zarena D, Wang G (2017) Host defense antimicrobial peptides as antibiotics: design and application strategies