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Cell Rep 27(1):22637.e4 [DOI] [PMC free article] [PubMed] [Google Scholar] 97.Beier UH, Angelin A, Akimova T, Wang L, Liu Y, et al

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Resistance to tyrosine kinase inhibitors in gastrointestinal stromal tumors

meningitidis (Exley et al., 2005), which metabolizes the lactate by at least three lactate dehydrogenases: two membrane-bound flavin mononucleotide-containing lactate dehydrogenases, LldD and LdhD, which catalyze the oxidation of L -lactate and D -lactate, respectively, and a soluble NAD + -dependent D -lactate dehydrogenase, LdhA (Erwin and Gotschlich, 1993, Erwin and Gotschlich, 1996