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It has been established that cerebral ischemic injury results in a core of necrotic tissue surrounded by a penumbra of tissue in which neurons are functionally inactive but still potentially viable [9]

Neurotropism of SARS-CoV-2 and neurological diseases of the central nervous system in COVID-19 patients

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IV acetylcysteine may be especially preferable because it achieves higher serum drug levels and avoids vomiting (of course, IV acetylcysteine is generally the treatment of choice regardless of pregnancy status)

Nature 466 , S6S7 (2010)