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doi: 10.1073/pnas.0506025102 46 DannR

Such ions can form metal complexes with A, promote A oligomerization, and potentially interact with Complex IV through a hemin-Cu-mediated dioxygen reduction reaction (Atwood et al., 2003

While clinical translation of HAGSH scaffolds remains in its formative stage, HA-based hydrogels have already demonstrated favorable safety profiles and therapeutic efficacy in chronic ulcer management, providing a strong clinical precedent

When activated, the complex plays an essential role in immune clearance through the facilitation of neutrophil adhesion to the endothelium, transmigration across the epithelia and phagocytosis of opsonized targets (131)

Chen X, Eslamfam S, Fang L, Qiao S, Ma X