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The restriction of calories will improve mitochondrial functions, leading to reduced ROS production and increased energy output

Liu L, Pan X, Xie F, Xu X, Xiao D, Xiao J, et al

A more recent, larger study confirmed these results, finding that the rate of isotretinoin-induced acne flaring dropped significantly from 30% in those who received isotretinoin alone down to 5% in the group that took isotretinoin plus levocetirizine 2

doi: 10.1080/14734220601142878

The Atlantic

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