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Safety in these populations cannot be assumed based on the existing trial data

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The latter, characterized by confusion, ataxia, and oculomotor abnormalities, highlights the importance of thiamine in preventing severe neurological complications (, )

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The high homocysteine level in LA most likely reflects its proatherogenic role in the pathogenesis of stroke, and may also explain the increased levels of cysteine and GSH in plasma, since a significant part of homocysteine is converted to cysteine, and the latter, in turn, is required for the formation of GSH