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For type 2 diabetes management, the medication may be needed long-term as diabetes is a chronic condition requiring ongoing treatment, though some patients may be able to reduce or discontinue medication if significant weight loss and lifestyle modifications lead to remission of their diabetes

The nanoparticle groups exhibited similar shape but the structure of polypeptides is highly influenced by the sample preparation steps (treatment with ethanol, drying steps) for electron microscopy imaging

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Davoine et al., 2006)