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Additionally, both cell lines exhibited a substantial reduction in cell viability and IC 50 values when treated with MNPs within the PM complexes under SMF exposure after 24 h ( Figurse 4B, D )

Interestingly, despite their resistance to ferroptosis, BV2 cells and PMs exhibit reduced inflammation by increasing the abundance of NRF2 protein

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Clinical validation of NR

The novel reagent 4-trimethylamino-6-(4-methoxy-1-naphthyl)-1,3,5-triazine-2-(3-aminophenylboronic acid (TMNTA) possesses aromatic rings within its molecular structure

Fink M, Abenhardt W, Ostermayr B, Berger M