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Additionally, GGCT mutants reversed this alteration, restoring [U- 13 C]-labeling of TCA metabolites and GSH

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GSSR represents a less concentrated form deriving from mixed disulfide formation with protein thiols (protein S-glutathionylation)

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Reciprocal interactions between neuro-inflammation and redox dysregulation/oxidative stress OxS and inflammation are reciprocally interconnected [138] and can activate each other

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Our results are further endorsed by the study conducted by Hamza et al

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13 Vitamin D deficiency: Vitamin D influences the expression of structural proteins (claudins and occludins) integral to gut barrier tight junctions, making adequate levels essential for intestinal integrity

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were the first to have used C

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