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Degen, G

coli BL21(DE3)

Hong Kong: Hai Feng Publishing Co., 1991:49-53

In animal models of inflammatory stimulation, Stevia extracts have been shown to downregulate the inhibitor of kappa B alpha (IB)/NF-B signaling pathway, inhibit the activation of IB kinase (IKK) and NF-B, and suppress the expression of inflammatory cytokines, including IL-6

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Approximately 2050 % of patients with SLE and 75 % of patients with RA eventually have cessation of the drug by 610 years of follow-up, mainly because of inefficacy in the case of RA and because of disease remission in the case of SLE [97, 115, 125, 128, 129]