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The prognosis is best for those detected early in life and treated appropriately, for those with a partial enzyme deficiency, and especially for those who are cobalamin responsive

Doses should be spaced evenly throughout the day (every three or four hours) preferably during or following meals and should be consumed slowly in order to maximize tolerance

Targeting these mechanisms may result in novel therapeutic approaches aimed at developing the means of effective prevention and treatment of the core ASD symptoms [11]