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Chiasson JL, Josse RG, Gomis R, et al

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[DOI] [PubMed] [Google Scholar] 241.Stege P.W., Sombra L.L., Messina G., Martinez L.D., Silva M.F

Although -oxidation is impaired in the setting of VPA toxicity, this metabolite has a prolonged elimination half-life and could be responsible for the prolonged coma that is sometimes observed despite the normalization in plasma VPA concentrations [17, 18]