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Description
E.MohamedS
doi: 10.1097/IN9.0000000000000030
New knowledge of the mechanisms of sorafenib resistance in liver cancer
In conjugates of the invention wherein the agent comprises a poly- or oligonucleotide, the pharmaceutically acceptable carrier preferably is a lipoplex system comprising at least one of cationic lipids or amphoteric lipids (as detailed inWO2002/066012), or a polyplex system comprising at least one of poly-L-Lysine, poly-L-ornithine, polyethyleneimine, and polyamidoamine
The other significantly elevated miRNAs included miR-192-3p, miR-27a, miR-335-5p, and miR-34a, all of which have previously been linked to liver fat accumulation, insulin resistance, and inflammation
Overall, GSTs have considerable agronomic potential not only in herbicide tolerance but also in heavy metal stress detoxification
