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PRM151, a recombinant form of human pentraxin2, also showed potential in IPF

In some cases, epitalon appeared to reduce tumor incidence in animal models

Tendon injuries pose significant challenges in clinical settings due to the complex structural, compositional, cellular, and biomechanical aspects involved in tendon healing

Additionally, SASP inhibits the amino acid transporter xCT, which reduced intracellular GSH levels, diminishes cellular antioxidant defense and induces ferroptosis in cancer cells (74)

G., Ai, W., Drenan, R

In HCECs applied with desiccating stress, the CEC ferroptosis was triggered by the aggregation of autophagy impairment-derived sequestosome 1 (SQSTM1), the overexpression of which fostered ferroptotic changes and substantially elevated ACSL4 (124)