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But in the DrugAge database, epithalamin is a super-star, with 15% life extension, and epitalon is a loser, with no average life extension whatever (in rodents)

It is of note that ROS levels did not increase during p16 induction of growth arrest (Figure 4D)

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The propensity of metal ions to coordinate with natural products is determined by a variety of chemical properties, including the charge density, electronic structure, and coordination geometry preference of the metal ion, as well as the electron-giving capacity and spatial configuration of the ligand in the natural product

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