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10.1016/j.celrep.2013.01.026 Cell Rep

Activation of the PI3K/Akt signaling pathway enhances eNOS expression and plays a regulatory role in eNOS
Baltimore, Md, USA: Williams & Wilkins

Chelation therapy is used in cases of increased toxic load, vascular disease or neurodegeneration
Increased BACH1 expression is observed in VSMCs in the mouse model of wireinjured femoral arteries

Since juglone, is a naphthoquinone, with known mechanisms of action ascribed to it, we have explored the possible mechanisms by which juglone might be inhibiting ChaC1
